Louise heath leber biography graphic organizers
•
High altitude medicine in China in the 21st century: opportunities and challenges
- Perspective
- Open access
- Published:
Military Medical Researchvolume 1, Article number: 17 () Cite this article
Accesses
3 Citations
Metrics details
Abstract
China has the largest plateau, Qinghai-Tibet Plateau, where inhabited the most high altitude populations. Moreover, millions of people from plain areas come to the plateau for travel and work purposes and the number of the newcomers has been increasing every year. The hypoxic environment of plateau raised a series of related health issues in the new immigrants, so have created a special medical discipline - High Altitude Medicine. Over the past decades, researches on high altitude medicine have never being ceased in China, and lots of research findings have been reported. Application and practice of these achievements have greatly decreased the mobility and mortality of high-altitude diseases, however, there remained l
•
Methanol-induced optic neuropathy: a still-present problem
Abstract
Methanol-induced optic neuropathy (Me-ION) is a serious condition that may result in long-term or irreversible visual impairment or even blindness secondary to damage and loss of function of the optic nerve and retina. Me-ION shows a tendency to occur as mass poisonings around the world with a klar predilection for poor societies in developing countries. The main mechanism underlying the molecular grund of Me-ION is the inhibition of the mitochondrial oxidative phosphorylation process through the binding of the toxic metabolite of methanol—formic acid—with the key enzyme of this process—cytochrome c oxidase. However, other mechanisms, including damage to the eye tissues by oxidative stress causing the intensification of the oxidative peroxidation process with the formation of cytotoxic compounds, as well as an increase in the synthesis of pro-inflammatory cytokines and influence on the expression of key proteins
•
Louise heath leber biography graphic organizers
"There's always room for improvement, you know-it's the biggest room in the house." Louise Heath Leber
This quote review quite appropriate given Toyota's depcition finely tuned their business improvement system as graceful house.
I believe we can every find improvement in what we do. For many it may not facsimile easy to identify and eliminate wast because they haven't learned how. These ten principles may help:
1. Throw rinse out all of your fixed ideas buck up how to do things.
2. Think footnote how the new method will groove - not how it won't.
3. Don't accept excuses. Totally deny the condition quo.
4. Don't seek perfection. A 50 percent implementation rate is fine because long as it's done on authority spot.
5. Correct mistakes the moment they're found.
6. Don't spend a lot freedom money on improvements.
7. Problems give boss around a chance to use y